TFGF-18

TFGF-18: Semisynthetic GSK-3β Inhibitor for Advanced Therapeutic Applications

TFGF-18 is a cutting-edge, semisynthetic inhibitor targeting Glycogen Synthase Kinase-3 Beta (GSK-3β), an enzyme critical in cellular signaling pathways involved in inflammation, cellular proliferation, and apoptosis. As a potent and selective GSK-3β inhibitor, TFGF-18 offers researchers a valuable tool for studying and modulating key biochemical pathways with applications in neurodegenerative diseases, cancer, diabetes, and psychiatric disorders. At Inland-chem, we have TFGF-18 for sale cheap. We are the best place if you want to buy TFGF-18. Order TFGF-18 now.

TFGF-18for sale Cheap

Synonym: TFGF-18; TFGF 18; TFGF8

IUPAC/Chemical Name: (2S,3S,4R,5R,6S)-6-(2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4-oxo-4H-chromen-6-yl)-3,4,5-trihydroxy-N-((S)-1,1,1-trifluoropropan-2-yl)tetrahydro-2H-pyran-2-carboxamide

Key Features:

• Selective Inhibition: Designed for high selectivity toward GSK-3β, reducing off-target effects and improving specificity in cell signaling studies.
• Enhanced Bioavailability: The semisynthetic structure of TFGF-18 enhances its stability and bioavailability, making it suitable for both in vitro and in vivo applications.
• Therapeutic Versatility: Targeting GSK-3β provides potential therapeutic applications in neuroprotection, anti-inflammation, cancer treatment, and metabolic regulation.

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Mechanism of Action: TFGF-18 binds to the active site of GSK-3β, inhibiting its ability to phosphorylate target substrates. This inhibition downregulates downstream effects linked to chronic diseases, including pathways associated with neuronal degradation, tumor progression, and insulin resistance.

Applications in Research:

• Neurodegenerative Diseases: By inhibiting GSK-3β, TFGF-18 shows potential in reducing β-amyloid production and tau phosphorylation, critical targets in Alzheimer’s research.
• Cancer Studies: GSK-3β is involved in cell cycle regulation and apoptosis; inhibiting it may help explore therapeutic strategies in oncology.
• Metabolic and Psychiatric Disorders: Inhibition of GSK-3β has shown promise in improving insulin sensitivity and mood stabilization, relevant for diabetes and bipolar disorder research.

Technical Specifications:

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Global Availability and Support TFGF-18 is available for worldwide shipping, ensuring access for researchers and institutions globally. inland-chem offers dedicated customer support for technical guidance, safety, and storage inquiries.