Coluracetam API Powder: What It Is, Uses, Buyers, and Specifications
Coluracetam API powder is a synthetic compound from the racetam family. It is also known as MKC-231 and has CAS number 135463-81-9. Its molecular formula is C19H23N3O3, while its molecular weight is 341.4 g/mol.
Researchers have studied coluracetam because of its effects on cholinergic neurotransmission. In particular, research has examined its ability to enhance high-affinity choline uptake. This mechanism has made the compound interesting in neuroscience and nootropic research.
However, coluracetam remains an investigational compound rather than an established mainstream medicine. Therefore, buyers should distinguish research-grade coluracetam API from an approved pharmaceutical product.
What Is Coluracetam API Powder?
Coluracetam is a synthetic small-molecule compound belonging to the racetam class of compounds. PubChem identifies it as a piracetam-type amide nootropic agent. The FDA Substance Registration System also lists coluracetam under the name COLURACETAM.
The term API means active pharmaceutical ingredient. Therefore, “coluracetam API powder” normally refers to the isolated chemical substance supplied as a powder for research, analytical, or pharmaceutical development purposes.
Coluracetam has several chemical identifiers. These identifiers help laboratories verify the identity of a material and distinguish it from related compounds.
Coluracetam Chemical Identity
The CAS number is 135463-81-9. Its FDA UNII is V6FL6O5GR7. Its PubChem Compound ID is 214346. The FDA record also lists MKC-231 as an alternative code name.
The compound has a molecular weight of approximately 341.4 g/mol. It contains carbon, hydrogen, nitrogen, and oxygen. PubChem reports an exact mass of approximately 341.1739 Da.
Coluracetam API Specification Table
| Specification | Coluracetam |
|---|---|
| Product name | Coluracetam |
| Common code | MKC-231 |
| CAS Number | 135463-81-9 |
| Molecular Formula | C19H23N3O3 |
| Molecular Weight | 341.4 g/mol |
| PubChem CID | 214346 |
| FDA UNII | V6FL6O5GR7 |
| Physical form | Powder |
| Compound class | Racetam |
| Stereochemistry | Achiral |
| Exact mass | 341.1739 Da |
| Research status | Investigational |
| Typical application | Scientific and pharmaceutical research |
The specifications above describe chemical identity. Commercial buyers should request a current Certificate of Analysis before accepting a batch.
What Is Coluracetam Used For?
Coluracetam has mainly attracted interest through experimental neuroscience research. Researchers have examined its interaction with cholinergic systems and its potential effects on cognitive processes.
One important research area involves high-affinity choline uptake. This process helps neurons obtain choline for acetylcholine production. Acetylcholine plays important roles in memory, learning, attention, and other neurological processes.
Because of this mechanism, researchers have investigated whether coluracetam could influence cognitive function. However, experimental activity does not establish a proven clinical benefit.
Coluracetam and Cognitive Research
Online nootropic communities often describe coluracetam as a cognitive enhancer. Such descriptions should not be confused with established medical indications.
Researchers have investigated racetam compounds for potential effects involving memory and cognition. However, the available evidence for coluracetam does not support treating it as an approved therapy for cognitive disorders.
Coluracetam has also received attention because of experimental research involving neurological and psychiatric conditions. Nevertheless, these investigations do not establish that consumers should use the compound for those conditions.
Coluracetam and Cholinergic Research
The compound is particularly interesting because researchers have studied its relationship with high-affinity choline uptake.
This distinguishes coluracetam from many other compounds discussed within the broader nootropic market. Instead of simply describing it as a generic “brain booster,” researchers can study its specific pharmacological properties.
Furthermore, laboratory research can help scientists understand how changes in cholinergic signaling may influence neurological functions.
At present, however, more evidence would be necessary before researchers could establish therapeutic effectiveness and long-term safety in humans.
Who Buys Coluracetam API Powder?
The main legitimate market for coluracetam powder consists of organizations involved in research, analytical testing, chemical development, and pharmaceutical research.
Potential professional buyers include research laboratories, pharmaceutical development companies, analytical laboratories, universities, and specialized chemical distributors.
Pharmaceutical Research Companies
Pharmaceutical research organizations may purchase small quantities for laboratory investigations. They can use reference material for analytical method development and experimental studies.
Such companies may also evaluate compounds during early-stage drug discovery programs. However, purchasing research material does not mean that the compound has regulatory approval for human treatment.
Universities and Research Laboratories
Academic laboratories may purchase coluracetam for neuroscience and pharmacology research. Researchers can study its chemical properties, biological interactions, and analytical characteristics.
Analytical laboratories may also need authenticated reference material for identification and testing.
Chemical and API Distributors
Specialized chemical distributors can supply research-grade compounds to qualified laboratories. These suppliers normally provide documentation such as a Certificate of Analysis, batch number, purity information, and analytical data.
Professional buyers should also verify manufacturing standards and applicable import regulations before ordering.
What Should Buyers Check Before Purchasing?
Quality verification is especially important when purchasing an investigational compound.
A buyer should request a Certificate of Analysis (CoA) for the exact batch. The document should identify the compound and provide analytical results.
HPLC testing can help evaluate chemical purity. Additional analytical techniques may include mass spectrometry, NMR, and other validated methods.
Important Quality Documents
A professional supplier should be able to provide appropriate documentation where applicable.
Important documents may include:
- Certificate of Analysis
- HPLC chromatogram
- Mass spectrometry data
- Batch or lot number
- Manufacturing date
- Retest or expiry information
- Safety Data Sheet
- Product specification sheet
- Packaging information
- Country of origin
The precise documentation depends on the intended application and jurisdiction.
Coluracetam API Powder: Research Status and Regulatory Considerations
Coluracetam should not be presented as an FDA-approved medicine simply because the FDA Substance Registration System contains a record for it.
The FDA explains that a substance appearing in its registration systems does not by itself demonstrate regulatory approval. FDA approval status should instead be checked through appropriate approval databases such as Drugs@FDA.
This distinction matters for commercial websites. Sellers should avoid unsupported statements claiming that coluracetam is an approved treatment for depression, anxiety, Alzheimer’s disease, dementia, or other medical conditions.
In addition, regulatory requirements can differ between countries. Importers and distributors should therefore check the applicable rules before commercializing or importing the substance.
The United States has also taken enforcement action involving the illegal marketing of coluracetam and other unapproved substances. This demonstrates why suppliers should carefully distinguish legitimate research materials from unauthorized medicinal products.
Why Is Coluracetam Interesting to Researchers?
Coluracetam remains scientifically interesting because it provides a tool for studying cholinergic mechanisms.
Researchers can investigate how modulation of choline uptake affects neuronal signaling. They can also examine the compound through pharmacological and analytical experiments.
Moreover, its defined molecular structure allows laboratories to develop analytical methods for identification and quality assessment.
However, scientific interest should not be confused with established clinical effectiveness.
Frequently Asked Questions About Coluracetam API Powder
Is coluracetam an API?
Coluracetam can be described as an active pharmaceutical ingredient or research chemical depending on its intended use and regulatory context. The term “API” does not automatically mean that the substance is approved for use in medicines.
What is the CAS number of coluracetam?
The CAS number listed for coluracetam is 135463-81-9. PubChem and the FDA Substance Registration System both identify this chemical.
What is the molecular formula of coluracetam?
The molecular formula is C19H23N3O3. Its molecular weight is approximately 341.4 g/mol.
Is coluracetam FDA approved?
A listing in an FDA substance database does not constitute FDA approval. Buyers should consult the official FDA drug approval databases when evaluating regulatory status.
Who purchases coluracetam powder?
Potential professional buyers include pharmaceutical researchers, universities, neuroscience laboratories, analytical laboratories, and specialized research-chemical distributors.
Conclusion
Coluracetam API powder is a synthetic racetam compound identified by CAS 135463-81-9 and molecular formula C19H23N3O3. Researchers have studied it particularly for its relationship with cholinergic signaling and high-affinity choline uptake.
The compound remains primarily relevant to experimental and research settings. Therefore, commercial descriptions should avoid presenting unproven therapeutic claims as established medical facts.
For professional procurement, buyers should focus on chemical identity, batch purity, analytical documentation, traceability, and applicable regulations.
A reliable supplier should provide appropriate quality documentation and clearly state the intended research use. Most importantly, buyers should verify regulatory requirements in the destination country before purchasing or importing coluracetam.
