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Fasoracetam API Powder
Fasoracetam API Powder: Uses, Properties, Buyers, and Research Overview
What Is Fasoracetam API Powder?
Fasoracetam is a synthetic compound from the racetam family.
Researchers also know it as NS-105 and NFC-1.
Its CAS number is 110958-19-5.
The compound has the formula C10H16N2O2.
Its reported molecular weight is 196.25 g/mol.
The term fasoracetam API powder usually refers to the active pharmaceutical ingredient.
In research settings, it may appear as a dry chemical powder.
However, API status does not mean that the material is an approved medicine.
PubChem identifies fasoracetam as an amino acid amide.
It also lists several development names and chemical identifiers.
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The compound has attracted interest in neuroscience research.
In particular, researchers have studied its relationship with mGluR signaling.
These receptors belong to the metabotropic glutamate receptor family.
Moreover, fasoracetam has entered human clinical research.
Clinical studies have examined it in specific neurological populations.
Therefore, it should not be described as a proven general-purpose nootropic.
Fasoracetam Chemical Identification
Several identifiers help laboratories verify fasoracetam materials.
The most common CAS number is 110958-19-5.
Its IUPAC name is also recorded by PubChem.
Fasoracetam also has an FDA substance identifier.
However, an FDA substance identifier does not mean FDA approval.
The FDA specifically states that UNII availability does not imply approval.
For procurement and laboratory work, identity remains important.
Therefore, buyers should compare the supplied material with its specification.
They should also review analytical documents before accepting a batch.
What Is Fasoracetam Used For?
Fasoracetam has mainly been studied as an investigational neuroscience compound.
Researchers have explored its effects on glutamatergic signaling.
They have also examined its relationship with metabotropic glutamate receptors.
Glutamate plays an important role in central nervous system signaling.
Meanwhile, mGluRs regulate several cellular signaling processes.
There are eight known mGluR subtypes across three main groups.
Fasoracetam research has therefore focused on this signaling system.
However, research interest does not establish a clinical indication.
Research Into ADHD and mGluR Signaling
One major area of research involves ADHD.
Clinical investigators have studied fasoracetam in adolescents with ADHD.
Some studies focused on genetic changes involving mGluR networks.
A Phase 2 study evaluated NFC-1 in adolescents.
The participants had genetic disorders affecting mGluR function.
The study assessed both efficacy and safety outcomes.
These studies are important for understanding research interest.
However, they do not establish fasoracetam as an approved ADHD treatment.
PubChem currently lists fasoracetam with a maximum clinical development phase of Phase 2.
It also links the compound to registered clinical research.
Research Into 22q11.2 Deletion Syndrome
More recently, fasoracetam has received regulatory research attention.
The FDA lists an orphan designation for fasoracetam monohydrate.
The designation concerns 22q11.2 deletion syndrome.
The designation was recorded on October 29, 2024.
However, the FDA database states that it is not FDA approved.
Therefore, commercial content should use accurate regulatory language.
Terms such as “investigational” and “research compound” are more suitable.
Claims of established treatment benefits should be avoided.
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Fasoracetam API Powder Specifications
Chemical specifications help laboratories identify and assess a material.
The following table summarizes commonly reported identity information.
| Specification | Fasoracetam |
|---|---|
| Product type | Research API / active compound |
| Common name | Fasoracetam |
| Other name | NS-105 |
| CAS number | 110958-19-5 |
| Molecular formula | C10H16N2O2 |
| Molecular weight | 196.25 g/mol |
| IUPAC name | (5R)-5-(piperidine-1-carbonyl)pyrrolidin-2-one |
| PubChem CID | 198695 |
| UNII | 42O8UF5CJB |
| ChEBI ID | CHEBI:31592 |
| ChEMBL ID | CHEMBL2106179 |
| Development status | Investigational |
| Clinical development | Phase 2 reported by PubChem |
The figures above describe the anhydrous compound.
Fasoracetam monohydrate has a different molecular weight.
PubChem reports 214.26 g/mol for the monohydrate.
Therefore, buyers should identify the exact material form.
They should not treat anhydrous and hydrated material as identical specifications.
Quality Testing for Fasoracetam API
Quality testing is especially important for research chemicals.
A reputable supplier should provide suitable analytical documentation.
For example, buyers may request a Certificate of Analysis.
Typical quality documentation can include:
- Identity testing
- Assay results
- Purity testing
- Residual solvent information
- Water content
- Heavy metal testing
- Microbiological information
- Batch and lot identification
- Storage information
Testing methods should match the intended research application.
For example, chromatography can help assess chemical purity.
Mass spectrometry can also support compound identification.
Furthermore, each batch should have traceable documentation.
This approach helps laboratories maintain reproducible research conditions.
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Who Buys Fasoracetam API Powder?
The market for fasoracetam API powder is primarily research-focused.
Different professional organizations may require the compound for laboratory work.
Pharmaceutical and Biotechnology Companies
Drug development companies may investigate fasoracetam during research.
They may study its pharmacology or formulation characteristics.
They may also evaluate its suitability for future development programs.
However, development status can change over time.
Therefore, companies should verify current regulatory information.
Universities and Research Institutes
Academic laboratories can also study fasoracetam.
Neuroscience groups may investigate glutamate signaling pathways.
Pharmacology groups may examine receptor-related mechanisms.
In addition, research institutions may use analytical methods.
Such work can involve compound characterization and laboratory comparison.
Contract Research Organizations
CROs may purchase research compounds for client projects.
Their work can include analytical and pharmacological investigations.
They may also support preclinical research programs.
However, requirements vary between projects.
Therefore, CRO buyers often request detailed specifications before purchasing.
Analytical and Chemical Laboratories
Analytical laboratories can use reference materials during testing.
They may investigate identity, purity, stability, or chemical behavior.
Likewise, specialist chemical companies may source research APIs.
These companies often require strong batch traceability and documentation.
What Should Buyers Check Before Sourcing?
When sourcing fasoracetam API powder, identity should come first.
The supplier should clearly state the chemical name and CAS number.
Next, buyers should examine the Certificate of Analysis.
The document should correspond to the supplied batch.
It should also include relevant testing results.
Furthermore, buyers should verify the material form.
This point matters because hydrate forms have different molecular weights.
Storage and packaging information also deserve attention.
Research chemicals require appropriate handling and controlled storage.
In addition, buyers should check applicable regulations.
Rules can differ between countries and intended applications.
Therefore, regulatory compliance should remain part of procurement planning.
Regulatory Status of Fasoracetam
Fasoracetam should not be presented as an FDA-approved medicine.
The FDA’s orphan designation database confirms its investigational status.
The FDA explains that investigational drugs are not approved products.
It also notes that safety and effectiveness remain under evaluation.
Consequently, marketing claims require careful wording.
A supplier should avoid unsupported therapeutic or disease-treatment claims.
Instead, accurate descriptions can focus on research use.
Examples include “research compound” and “investigational API.”
Conclusion
Fasoracetam API powder is a specialized neuroscience research compound.
It is also known by names such as NS-105 and NFC-1.
Its common CAS number is 110958-19-5.
Research has examined fasoracetam and mGluR-related signaling.
Clinical studies have also explored specific neurological populations.
However, the compound remains investigational.
Therefore, accurate product information is essential for professional buyers.
Buyers should verify identity, purity, batch data, and regulatory requirements.
They should also distinguish anhydrous fasoracetam from its monohydrate form.
For research organizations, documentation supports reliable laboratory work.
Moreover, transparent specifications can improve supplier and buyer communication.
References and Further Reading
- PubChem — Fasoracetam compound record
- FDA — Fasoracetam Orphan Designation
- ClinicalTrials.gov — Fasoracetam ADHD study
- FDA — Investigational Drug Information
- PubChem — Fasoracetam Monohydrate
